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Role of Drug Metabolism in the Cytotoxicity and Clinical Efficacy of Anthracyclines

Many clinical studies involving anti-tumor agents neglect to consider how these agents are metabolized within the host and whether the creation of specific metabolites alters drug therapeutic properties or toxic side effects. However, this is not the case for the anthracycline class of chemotherapy...

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Detalhes bibliográficos
Publicado no:Curr Drug Metab
Main Authors: Edwardson, Derek W., Narendrula, Rashmi, Chewchuk, Simon, Mispel-Beyer, Kyle, Mapletoft, Jonathan P.J., Parissenti, Amadeo M.
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398089/
https://ncbi.nlm.nih.gov/pubmed/26321196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1389200216888150915112039
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