Genome-wide search for candidate genes for yeast robustness improvement against formic acid reveals novel susceptibility (Trk1 and positive regulators) and resistance (Haa1-regulon) determinants

BACKGROUND: Formic acid is an inhibitory compound present in lignocellulosic hydrolysates. Understanding the complex molecular mechanisms underlying Saccharomyces cerevisiae tolerance to this weak acid at the system level is instrumental to guide synthetic pathway engineering for robustness improvem...

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Vydáno v:Biotechnol Biofuels
Hlavní autoři: Henriques, Sílvia F., Mira, Nuno P., Sá-Correia, Isabel
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395885/
https://ncbi.nlm.nih.gov/pubmed/28428821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13068-017-0781-5
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