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Genome-wide search for candidate genes for yeast robustness improvement against formic acid reveals novel susceptibility (Trk1 and positive regulators) and resistance (Haa1-regulon) determinants

BACKGROUND: Formic acid is an inhibitory compound present in lignocellulosic hydrolysates. Understanding the complex molecular mechanisms underlying Saccharomyces cerevisiae tolerance to this weak acid at the system level is instrumental to guide synthetic pathway engineering for robustness improvem...

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Publicado en:Biotechnol Biofuels
Main Authors: Henriques, Sílvia F., Mira, Nuno P., Sá-Correia, Isabel
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395885/
https://ncbi.nlm.nih.gov/pubmed/28428821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13068-017-0781-5
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