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Genetic Analysis of the Neuronal and Ubiquitous AP-3 Adaptor Complexes Reveals Divergent Functions in Brain

Neurons express adaptor (AP)-3 complexes assembled with either ubiquitous (β3A) or neuronal-specific (β3B) β3 isoforms. However, it is unknown whether these complexes indeed perform distinct functions in neuronal tissue. Here, we explore this hypothesis by using genetically engineered mouse models l...

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Hlavní autoři: Seong, E., Wainer, B. H., Hughes, E. D., Saunders, T. L., Burmeister, M., Faundez, V.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC539158/
https://ncbi.nlm.nih.gov/pubmed/15537701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-10-0892
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