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Enhanced non-viral gene delivery by coordinated endosomal release and inhibition of β-tubulin deactylase

Efficient non-viral gene delivery is highly desirable but often unattainable with some cell-types. We report here that non-viral DNA polyplexes can efficiently transfect differentiated neuronal and stem cells. Polyplex transfection centrifugation protocols was enhanced by including a simultaneous tr...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Ho, Yoon Khei, Zhou, Li Han, Tam, Kam C., Too, Heng Phon
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389648/
https://ncbi.nlm.nih.gov/pubmed/27899629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1143
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