sCD163 levels as a biomarker of disease severity in leprosy and visceral leishmaniasis

BACKGROUND: CD163, receptor for the haptoglobin–hemoglobin complex, is expressed on monocytes/macrophages and neutrophils. A soluble form of CD163 (sCD163) has been associated with the M2 macrophage phenotype, and M2 macrophages have been shown to down-modulate inflammatory responses. In particular,...

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Bibliographic Details
Published in:PLoS Negl Trop Dis
Main Authors: Silva, Ricardo Luís Louzada, Santos, Marcio B., Almeida, Priscila L. S., Barros, Thayse S., Magalhães, Lucas, Cazzaniga, Rodrigo A., Souza, Patrícia R. M., Luz, Nívea F., França-Costa, Jaqueline, Borges, Valeria M., Lima-Junior, Djalma S., Lipscomb, Michael W., Duthie, Malcolm S., Reed, Steven G., Almeida, Roque Pacheco, Jesus, Amélia Ribeiro
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386291/
https://ncbi.nlm.nih.gov/pubmed/28355218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005486
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