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In vivo detection of lateral–ventral tier nigral degeneration in Parkinson's disease

The objective of this study was to measure neuromelanin‐sensitive MRI contrast changes in the lateral‐ventral tier of substantia nigra pars compacta in Parkinson's disease (PD). Histopathological studies of PD have demonstrated both massive loss of melanized dopamine neurons and iron accumulati...

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Detalhes bibliográficos
Publicado no:Hum Brain Mapp
Main Authors: Huddleston, Daniel E., Langley, Jason, Sedlacik, Jan, Boelmans, Kai, Factor, Stewart A., Hu, Xiaoping P.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385149/
https://ncbi.nlm.nih.gov/pubmed/28240402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hbm.23547
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