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Assessing gene-environment interaction effects of FTO, MC4R and lifestyle factors on obesity using an extreme phenotype sampling design: Results from the HUNT study

BACKGROUND: Our aim was to assess the influence of age, gender and lifestyle factors on the effect of the obesity-promoting alleles of FTO and MCR4. METHODS: The HUNT study comprises health information on the population of Nord-Trøndelag county, Norway. Extreme phenotype participants (gender-wise lo...

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Vydáno v:PLoS One
Hlavní autoři: Bjørnland, Thea, Langaas, Mette, Grill, Valdemar, Mostad, Ingrid Løvold
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383228/
https://ncbi.nlm.nih.gov/pubmed/28384342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175071
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