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A Common Genetic Variant Risk Score Is Associated with Drug-Induced QT Prolongation and Torsade de Pointes Risk: a Pilot Study
BACKGROUND: Drug-induced QT interval prolongation, a risk factor for life-threatening ventricular arrhythmias, is a potential side effect of many marketed and withdrawn medications. The contribution of common genetic variants previously associated with baseline QT interval to drug-induced QT prolong...
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| Опубликовано в: : | Circulation |
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| Главные авторы: | , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5380476/ https://ncbi.nlm.nih.gov/pubmed/28213480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.116.023980 |
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