Unique spectral signatures of the nucleic acid dye acridine orange can distinguish cell death by apoptosis and necroptosis

Cellular injury and death are ubiquitous features of disease, yet tools to detect them are limited and insensitive to subtle pathological changes. Acridine orange (AO), a nucleic acid dye with unique spectral properties, enables real-time measurement of RNA and DNA as proxies for cell viability duri...

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Bibliografiska uppgifter
I publikationen:J Cell Biol
Huvudupphovsmän: Plemel, Jason R., Caprariello, Andrew V., Keough, Michael B., Henry, Tyler J., Tsutsui, Shigeki, Chu, Tak H., Schenk, Geert J., Klaver, Roel, Yong, V. Wee, Stys, Peter K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2017
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379938/
https://ncbi.nlm.nih.gov/pubmed/28264914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201602028
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