Dexmedetomidine ameliorates muscle wasting and attenuates the alteration of hypothalamic neuropeptides and inflammation in endotoxemic rats

Dexmedetomidine is generally used for sedaton in critically ill, it could shorten duration of mechanical ventilation, ICU stay and lower basic metabolism. However, the exact mechanism of these positive effects remains unkown. Here we investigated the hypothesis that dexmedetomidine could ameliorate...

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Bibliographic Details
Published in:PLoS One
Main Authors: Cheng, Minhua, Gao, Tao, Xi, Fengchan, Cao, Chun, Chen, Yan, Zhao, Chenyan, Li, Qiurong, Yu, Wenkui
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373637/
https://ncbi.nlm.nih.gov/pubmed/28358856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174894
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