Present Molecular Limitations of ON-Bipolar Cell Targeted Gene Therapy

Recent studies have demonstrated the safety and efficacy of ocular gene therapy based on adeno-associated viral vectors (AAVs). Accordingly, a surge in promising new gene therapies is entering clinical trials, including the first optogenetic therapy for vision restoration. To date, optogenetic thera...

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Bibliographic Details
Published in:Front Neurosci
Main Authors: van Wyk, Michiel, Hulliger, Elmar C., Girod, Lara, Ebneter, Andreas, Kleinlogel, Sonja
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372788/
https://ncbi.nlm.nih.gov/pubmed/28424574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00161
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