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The interaction between acetylation and serine-574 phosphorylation regulates the apoptotic function of FOXO3

The multispecific transcription factor and tumor suppressor FOXO3 is an important mediator of apoptosis, but the mechanisms that control its proapoptotic function are poorly understood. There has long been evidence that acetylation promotes FOXO3-driven apoptosis and recently a specific JNK (c-Jun N...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Li, Z, Bridges, B, Olson, J, Weinman, SA
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5366279/
https://ncbi.nlm.nih.gov/pubmed/27669435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.359
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