A multi species evaluation of the radiation dosimetry of [(11)C]erlotinib, the radiolabeled analog of a clinically utilized tyrosine kinase inhibitor

INTRODUCTION: Erlotinib is a tyrosine kinase inhibitor prescribed for non-small cell lung cancer patients bearing epidermal growth factor receptor mutations in the kinase domain. The objectives of this study were to (1) establish a human dosimetry profile of [(11)C]erlotinib and (2) assess the consi...

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Vydáno v:Nucl Med Biol
Hlavní autoři: Petrulli, J. Ryan, Hansen, Søren B., Abourbeh, Galith, Yaqub, Maqsood, Bahce, Idris, Holden, Daniel, Huang, Yiyun, Nabulsi, Nabeel B., Contessa, Joseph N., Mishani, Eyal, Lammertsma, Adriaan A., Morris, Evan D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360653/
https://ncbi.nlm.nih.gov/pubmed/28126682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2016.12.009
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