Epigenetic silencing of TET2 and TET3 induces an EMT-like process in melanoma

Epithelial-Mesenchymal Transition (EMT) is a critical step in the progression of cancer. Malignant melanoma, a cancer developed from pigmented melanocytes, metastasizes through an EMT-like process. Ten-eleven translocation (TET) enzymes, catalyzing the conversion of 5-methylcytosine (5mC) to 5-hydro...

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Udgivet i:Oncotarget
Main Authors: Gong, Fuxing, Guo, Yu, Niu, Yiqian, Jin, Jiawei, Zhang, Xiaojuan, Shi, Xiaoqian, Zhang, Limeng, Li, Runting, Chen, Longxin, Ma, Runlin Z.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352122/
https://ncbi.nlm.nih.gov/pubmed/27852070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13324
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