Wee1 and Cdc25 are controlled by conserved PP2A-dependent mechanisms in fission yeast

Wee1 and Cdc25 are conserved regulators of mitosis. Wee1 is a kinase that delays mitosis via inhibitory phosphorylation of Cdk1, while Cdc25 is a phosphatase that promotes mitosis by removing the inhibitory phosphorylation. Although Wee1 and Cdc25 are conserved proteins, it has remained unclear whet...

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Veröffentlicht in:Cell Cycle
Hauptverfasser: Lucena, Rafael, Alcaide-Gavilán, Maria, Anastasia, Steph D., Kellogg, Douglas R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351916/
https://ncbi.nlm.nih.gov/pubmed/28103117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1281476
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