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Translational termination without a stop codon
Ribosomes stall when they encounter the end of mRNA without an in-frame stop codon. In bacteria, these nonstop complexes can be rescued by alternative ribosome-rescue factor A (ArfA). Here, using electron cryomicroscopy, we have determined structures of ArfA bound to the ribosome with 3′-truncated m...
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| Gepubliceerd in: | Science |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5351859/ https://ncbi.nlm.nih.gov/pubmed/27934701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aai9127 |
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