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Translational termination without a stop codon

Ribosomes stall when they encounter the end of mRNA without an in-frame stop codon. In bacteria, these nonstop complexes can be rescued by alternative ribosome-rescue factor A (ArfA). Here, using electron cryomicroscopy, we have determined structures of ArfA bound to the ribosome with 3′-truncated m...

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Bibliographic Details
Published in:Science
Main Authors: James, Nathan R., Brown, Alan, Gordiyenko, Yuliya, Ramakrishnan, V.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351859/
https://ncbi.nlm.nih.gov/pubmed/27934701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aai9127
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