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Subcellular localization of FOXO3a as a potential biomarker of response to combined treatment with inhibitors of PI3K and autophagy in PIK3CA-mutant cancer cells

Autophagy is the process of lysosome-mediated degradation and recycling that functions as an adaptive survival mechanism during anti-cancer therapy. Aberrant activation of the phosphoinositide-3-kinase (PI3K) pathway frequently occurs in solid tumors, including cervical cancer. However, single-agent...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Kim, Hyun-Jung, Lee Yoon, Soo, Young, Chan Kim, Hwan, Yun Kim, Ju, Woong, Cheol, Seung Kim
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351656/
https://ncbi.nlm.nih.gov/pubmed/28036259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14245
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