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Structural Modification of the Designer Stimulant α-Pyrrolidinovalerophenone (α-PVP) Influences Potency at Dopamine Transporters

α-Pyrrolidinovalerophenone (α-PVP, 7) is an illegal synthetic stimulant that is being sold on the clandestine market as “flakka” and “gravel”. The potent pharmacological effects of α-PVP are presumably mediated by inhibition of dopamine uptake at the dopamine transporter (DAT). However, little is kn...

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Detalhes bibliográficos
Publicado no:ACS Chem Neurosci
Main Authors: Kolanos, R., Sakloth, F., Jain, A. D., Partilla, J. S., Baumann, M. H., Glennon, R. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349767/
https://ncbi.nlm.nih.gov/pubmed/26217965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.5b00160
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