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E4 Ligase Specific Ubiquitylation Hubs Coordinate DNA Double Strand Break Repair and Apoptosis

The repair of DNA double strand breaks (DSBs) requires tight regulation with the DNA damage response that mediates apoptotic death of damaged cells. Multiple protein ubiquitylation events at the sites of DSBs regulate damage recognition, repair, and signalling processes. However, the spatiotemporal...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nat Struct Mol Biol
Päätekijät: Ackermann, Leena, Schell, Michael, Pokrzywa, Wojciech, Kevei, Éva, Gartner, Anton, Schumacher, Björn, Hoppe, Thorsten
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349472/
https://ncbi.nlm.nih.gov/pubmed/27669035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3296
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