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E4 Ligase Specific Ubiquitylation Hubs Coordinate DNA Double Strand Break Repair and Apoptosis

The repair of DNA double strand breaks (DSBs) requires tight regulation with the DNA damage response that mediates apoptotic death of damaged cells. Multiple protein ubiquitylation events at the sites of DSBs regulate damage recognition, repair, and signalling processes. However, the spatiotemporal...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Struct Mol Biol
Egile Nagusiak: Ackermann, Leena, Schell, Michael, Pokrzywa, Wojciech, Kevei, Éva, Gartner, Anton, Schumacher, Björn, Hoppe, Thorsten
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349472/
https://ncbi.nlm.nih.gov/pubmed/27669035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3296
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