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E4 Ligase Specific Ubiquitylation Hubs Coordinate DNA Double Strand Break Repair and Apoptosis
The repair of DNA double strand breaks (DSBs) requires tight regulation with the DNA damage response that mediates apoptotic death of damaged cells. Multiple protein ubiquitylation events at the sites of DSBs regulate damage recognition, repair, and signalling processes. However, the spatiotemporal...
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| Опубликовано в: : | Nat Struct Mol Biol |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5349472/ https://ncbi.nlm.nih.gov/pubmed/27669035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3296 |
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