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Failures and Successes of NMDA Receptor Antagonists: Molecular Basis for the Use of Open-Channel Blockers like Memantine in the Treatment of Acute and Chronic Neurologic Insults

Summary: Excitotoxicity, defined as excessive exposure to the neurotransmitter glutamate or overstimulation of its membrane receptors, has been implicated as one of the key factors contributing to neuronal injury and death in a wide range of both acute and chronic neurologic disorders. Excitotoxic c...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριος συγγραφέας: Lipton, Stuart A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The American Society for Experimental NeuroTherapeutics, Inc. 2004
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC534915/
https://ncbi.nlm.nih.gov/pubmed/15717010
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