Isoniazid clearance is impaired among human immunodeficiency virus/tuberculosis patients with high levels of immune activation

AIMS: Immune activation, which is characteristic of both tuberculosis (TB) and human immunodeficiency virus (HIV) infection, is associated with impaired drug metabolism. We tested the hypothesis that elevated levels of systemic immune activation among adults with HIV/TB initiating antiretroviral the...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Vinnard, Christopher, Ravimohan, Shruthi, Tamuhla, Neo, Ivaturi, Vijay, Pasipanodya, Jotam, Srivastava, Shashikant, Modongo, Chawangwa, Zetola, Nicola M., Weissman, Drew, Gumbo, Tawanda, Bisson, Gregory P.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346858/
https://ncbi.nlm.nih.gov/pubmed/27792837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13172
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