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Heat Shock Factor 1 Depletion Sensitizes A172 Glioblastoma Cells to Temozolomide via Suppression of Cancer Stem Cell-Like Properties

Heat shock factor 1 (HSF1), a transcription factor activated by various stressors, regulates proliferation and apoptosis by inducing expression of target genes, such as heat shock proteins and Bcl-2 (B-cell lymphoma 2) interacting cell death suppressor (BIS). HSF1 also directly interacts with BIS, a...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Im, Chang-Nim, Yun, Hye Hyeon, Lee, Jeong-Hwa
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344000/
https://ncbi.nlm.nih.gov/pubmed/28241425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18020468
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