Safer topical treatment for inflammation using 5α-tetrahydrocorticosterone in mouse models

Use of topical glucocorticoid for inflammatory skin conditions is limited by systemic and local side-effects. This investigation addressed the hypothesis that topical 5α-tetrahydrocorticosterone (5αTHB, a corticosterone metabolite) inhibits dermal inflammation without affecting processes responsible...

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Gepubliceerd in:Biochem Pharmacol
Hoofdauteurs: Gastaldello, Annalisa, Livingstone, Dawn E.W., Abernethie, Amber J., Tsang, Nicola, Walker, Brian R., Hadoke, Patrick W.F., Andrew, Ruth
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier Science 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342892/
https://ncbi.nlm.nih.gov/pubmed/28131845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.01.008
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