Hypoxia-targeted (131)I therapy of hepatocellular cancer after systemic mesenchymal stem cell-mediated sodium iodide symporter gene delivery

Adoptively transferred mesenchymal stem cells (MSCs) home to solid tumors. Biologic features within the tumor environment can be used to selectively activate transgenes in engineered MSCs after tumor invasion. One of the characteristic features of solid tumors is hypoxia. We evaluated a hypoxia-base...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Müller, Andrea M., Schmohl, Kathrin A., Knoop, Kerstin, Schug, Christina, Urnauer, Sarah, Hagenhoff, Anna, Clevert, Dirk-André, Ingrisch, Michael, Niess, Hanno, Carlsen, Janette, Zach, Christian, Wagner, Ernst, Bartenstein, Peter, Nelson, Peter J., Spitzweg, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342382/
https://ncbi.nlm.nih.gov/pubmed/27458162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10758
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