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DNA repair and replication links to pluripotency and differentiation capacity of pig iPS cells

Pigs are proposed to be suitable large animal models for test of the efficacy and safety of induced pluripotent stem cells (iPSCs) for stem cell therapy, but authentic pig ES/iPS cell lines with germline competence are rarely produced. The pathways or signaling underlying the defective competent pig...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Liu, Kai, Mao, Jian, Song, Lipu, Fan, Anran, Zhang, Sheng, Wang, Jianyu, Fan, Nana, Liu, Na, Ye, Xiaoying, Fu, Haifeng, Zhou, Zhongcheng, Wang, Yong, Wei, Hong, Liu, Zhonghua, Li, Ziyi, Lai, Liangxue, Wang, Xumin, Liu, Lin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333863/
https://ncbi.nlm.nih.gov/pubmed/28253351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173047
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