Acid-Sensitive Sheddable PEGylated PLGA Nanoparticles Increase the Delivery of TNF-α siRNA in Chronic Inflammation Sites

There has been growing interest in utilizing small interfering RNA (siRNA) specific to pro-inflammatory cytokines, such as tumor necrosis factor-α ( TNF-α), in chronic inflammation therapy. However, delivery systems that can increase the distribution of the siRNA in chronic inflammation sites after...

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Detalles Bibliográficos
Publicado en:Mol Ther Nucleic Acids
Autores principales: Aldayel, Abdulaziz M, Naguib, Youssef W, O'Mary, Hannah L, Li, Xu, Niu, Mengmeng, Ruwona, Tinashe B, Cui, Zhengrong
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330937/
https://ncbi.nlm.nih.gov/pubmed/27434685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.39
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