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p53 switches off pluripotency on differentiation

The role of p53 as “a guardian of the genome” has been well established in somatic cells. However, its role in pluripotent stem cells remains much more elusive. Here, we discuss research progress in understanding the role of p53 in pluripotent stem cells and in pluripotent stem cell-like cancer stem...

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Detalles Bibliográficos
Publicado en:Stem Cell Res Ther
Main Authors: Lin, Tongxiang, Lin, Yi
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330084/
https://ncbi.nlm.nih.gov/pubmed/28241890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0498-1
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