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p53 switches off pluripotency on differentiation

The role of p53 as “a guardian of the genome” has been well established in somatic cells. However, its role in pluripotent stem cells remains much more elusive. Here, we discuss research progress in understanding the role of p53 in pluripotent stem cells and in pluripotent stem cell-like cancer stem...

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Détails bibliographiques
Publié dans:Stem Cell Res Ther
Auteurs principaux: Lin, Tongxiang, Lin, Yi
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330084/
https://ncbi.nlm.nih.gov/pubmed/28241890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0498-1
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