CXCL12 protects pancreatic β-cells from oxidative stress by a Nrf2-induced increase in catalase expression and activity

Due to intrinsically low levels of antioxidant enzyme expression and activity, insulin producing pancreatic β-cells are particularly susceptible to free radical attack. In diabetes mellitus, which is accompanied by high levels of oxidative stress, this feature of β-cells significantly contributes to...

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Bibliografiska uppgifter
I publikationen:Proc Jpn Acad Ser B Phys Biol Sci
Huvudupphovsmän: DINIĆ, Svetlana, GRDOVIĆ, Nevena, USKOKOVIĆ, Aleksandra, ĐORĐEVIĆ, Miloš, MIHAILOVIĆ, Mirjana, JOVANOVIĆ, Jelena Arambašić, POZNANOVIĆ, Goran, VIDAKOVIĆ, Melita
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Japan Academy 2016
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328787/
https://ncbi.nlm.nih.gov/pubmed/27840391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2183/pjab.92.436
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