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CXCL12 protects pancreatic β-cells from oxidative stress by a Nrf2-induced increase in catalase expression and activity
Due to intrinsically low levels of antioxidant enzyme expression and activity, insulin producing pancreatic β-cells are particularly susceptible to free radical attack. In diabetes mellitus, which is accompanied by high levels of oxidative stress, this feature of β-cells significantly contributes to...
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| Publié dans: | Proc Jpn Acad Ser B Phys Biol Sci |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Japan Academy
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5328787/ https://ncbi.nlm.nih.gov/pubmed/27840391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2183/pjab.92.436 |
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