Hydrocephalus and arthrogryposis in an immunocompetent mouse model of ZIKA teratogeny: A developmental study

The teratogenic mechanisms triggered by ZIKV are still obscure due to the lack of a suitable animal model. Here we present a mouse model of developmental disruption induced by ZIKV hematogenic infection. The model utilizes immunocompetent animals from wild-type FVB/NJ and C57BL/6J strains, providing...

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Udgivet i:PLoS Negl Trop Dis
Main Authors: Xavier-Neto, Jose, Carvalho, Murilo, Pascoalino, Bruno dos Santos, Cardoso, Alisson Campos, Costa, Ângela Maria Sousa, Pereira, Ana Helena Macedo, Santos, Luana Nunes, Saito, Ângela, Marques, Rafael Elias, Smetana, Juliana Helena Costa, Consonni, Silvio Roberto, Bandeira, Carla, Costa, Vivian Vasconcelos, Bajgelman, Marcio Chaim, de Oliveira, Paulo Sérgio Lopes, Cordeiro, Marli Tenorio, Gonzales Gil, Laura Helena Vega, Pauletti, Bianca Alves, Granato, Daniela Campos, Paes Leme, Adriana Franco, Freitas-Junior, Lucio, Holanda de Freitas, Carolina Borsoi Moraes, Teixeira, Mauro Martins, Bevilacqua, Estela, Franchini, Kleber
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322881/
https://ncbi.nlm.nih.gov/pubmed/28231241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005363
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