Secretory phospholipase A2 in the pathogenesis of acute dengue infection

INTRODUCTION: Platelet activating factor (PAF) is an important mediator of vascular leak in acute dengue. Phospholipase A2s (PLA2) are inflammatory lipid enzymes that generate and regulate PAF and other mediators associated with mast cells. We sought to investigate if mast cell activation and increa...

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Bibliographic Details
Published in:Immun Inflamm Dis
Main Authors: Jeewandara, Chandima, Gomes, Laksiri, Udari, Sukhitha, Paranavitane, S.A., Shyamali, N.L.A., Ogg, Graham S., Malavige, Gathsaurie Neelika
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322161/
https://ncbi.nlm.nih.gov/pubmed/28250920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.135
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