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Dynamics of GreB-RNA polymerase interaction allow a proofreading accessory protein to patrol for transcription complexes needing rescue
The secondary channel (SC) of multisubunit RNA polymerases (RNAPs) allows access to the active site and is a nexus for the regulation of transcription. Multiple regulatory proteins bind in the SC and reprogram the catalytic activity of RNAP, but the dynamics of these factors’ interactions with RNAP...
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Publicat a: | Proc Natl Acad Sci U S A |
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Autors principals: | , , , , , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
National Academy of Sciences
2017
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5320998/ https://ncbi.nlm.nih.gov/pubmed/28137878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616525114 |
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