Dendritic cells derived exosomes migration to spleen and induction of inflammation are regulated by CCR7

Mature dendritic cells (DCs) home to secondary lymphoid organs through CC chemokine receptor 7 (CCR7). Exosomes derived from DCs (DC-exos) are reported to migrate to spleen and induce inflammation in vivo. In this study, we demonstrated that mature bone marrow DC-exos can activate immature DC and T...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wei, Gao, Jie, Yuan, Haibo, Liu, Chaoneng, Wu, Dong, Huang, Jianbing, Zhu, Junjie, Guo, Leilei, Ma, Hongtao, Shi, Yunzeng, Zou, Junbo, Ge
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320445/
https://ncbi.nlm.nih.gov/pubmed/28223684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42996
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