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Molecular determinants of KA1 domain-mediated autoinhibition and phospholipid activation of MARK1 kinase
Protein kinases are frequently regulated by intramolecular autoinhibitory interactions between protein modules that are reversed when these modules bind other ‘activating’ protein or membrane-bound targets. One group of kinases, the MAP/microtubule affinity-regulating kinases (MARKs) contain a poorl...
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| Publicado no: | Biochem J |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5317272/ https://ncbi.nlm.nih.gov/pubmed/27879374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160792 |
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