Heterogeneous dimer peptide-conjugated polylysine dendrimer-Fe(3)O(4) composite as a novel nanoscale molecular probe for early diagnosis and therapy in hepatocellular carcinoma

A novel nanoscale molecular probe is formulated in order to reduce toxicity and side effects of antitumor drug doxorubicin (DOX) in normal tissues and to enhance the detection sensitivity during early imaging diagnosis. The mechanism involves a specific targeting of Arg-Gly-Asp peptide (RGD)-GX1 het...

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Bibliografische gegevens
Gepubliceerd in:Int J Nanomedicine
Hoofdauteurs: Shen, Jian-Min, Li, Xin-Xin, Fan, Lin-Lan, Zhou, Xing, Han, Ji-Min, Jia, Ming-Kang, Wu, Liang-Fan, Zhang, Xiao-Xue, Chen, Jing
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove Medical Press 2017
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5315215/
https://ncbi.nlm.nih.gov/pubmed/28243083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S126887
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