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Plasma-derived parasitic microRNAs have insufficient concentrations to be used as diagnostic biomarker for detection of Onchocerca volvulus infection or treatment monitoring using LNA-based RT-qPCR

River blindness, caused by infection with the filarial nematode Onchocerca volvulus, is a neglected tropical disease affecting millions of people. There is a clear need for diagnostic tools capable of identifying infected patients, but that can also be used for monitoring disease progression and tre...

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Bibliographische Detailangaben
Veröffentlicht in:Parasitol Res
Hauptverfasser: Lagatie, Ole, Batsa Debrah, Linda, Debrah, Alex, Stuyver, Lieven J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313568/
https://ncbi.nlm.nih.gov/pubmed/28111713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00436-017-5382-5
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