FOXM1 confers resistance to gefitinib in lung adenocarcinoma via a MET/AKT-dependent positive feedback loop

Gefitinib resistance remains a major problem in the treatment of lung adenocarcinoma. However, the molecular mechanisms of gefitinib resistance are not fully understood. In this study, we characterized the critical role of transcription factor Forkhead box protein M1 (FOXM1) in gefitinib resistance...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Yu, Zhang, Weiwei, Wen, Li, Yang, Huiling, Wen, Mingling, Yun, Yuyu, Zhao, Lisheng, Zhu, Xiaofei, Tian, Li, Luo, Erping, Li, Yu, Liu, Wenchao, Wen, Ning
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312309/
https://ncbi.nlm.nih.gov/pubmed/27494877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11043
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