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The TNF-α antagonist etanercept reverses age-related decreases in colonic SERT expression and faecal output in mice
Treatment for chronic constipation in older people is challenging and the condition has a major impact on quality of life. A lack of understanding about the causes of this condition has hampered the development of effective treatments. 5-HT is an important pro-kinetic agent in the colon. We examined...
Guardat en:
| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5309893/ https://ncbi.nlm.nih.gov/pubmed/28198447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42754 |
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