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Phenotypic consequences of somatic mutations in the ataxia-telangiectasia mutated gene in non-small cell lung cancer
Mutations in the Ataxia-telangiectasia mutated (ATM) gene are frequently found in human cancers, including non-small cell lung cancer (NSCLC). Loss of ATM function confers sensitivity to ionising radiation (IR) and topoisomerase inhibitors and may thus define a subset of cancer patients that could g...
Shranjeno v:
izdano v: | Oncotarget |
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Main Authors: | , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Impact Journals LLC
2016
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5308618/ https://ncbi.nlm.nih.gov/pubmed/27602502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11845 |
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