Sputum DNA sequencing in cystic fibrosis: non-invasive access to the lung microbiome and to pathogen details

BACKGROUND: Cystic fibrosis (CF) is a life-threatening genetic disorder, characterized by chronic microbial lung infections due to abnormally viscous mucus secretions within airways. The clinical management of CF typically involves regular respiratory-tract cultures in order to identify pathogens an...

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Udgivet i:Microbiome
Main Authors: Feigelman, Rounak, Kahlert, Christian R., Baty, Florent, Rassouli, Frank, Kleiner, Rebekka L., Kohler, Philipp, Brutsche, Martin H., von Mering, Christian
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5303297/
https://ncbi.nlm.nih.gov/pubmed/28187782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40168-017-0234-1
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