Simultaneous activation and inhibition of autophagy sensitizes cancer cells to chemotherapy

While combined chemotherapy (CT) with an autophagy inducer and an autophagy inhibitor appears paradoxical, it may provide a more effective perturbation of autophagy pathways. We used two dissimilar cell lines to test the hypothesis that autophagy is the common denominator of cell fate after CT. HA22...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Chi, Kwan-Hwa, Wang, Yu-Shan, Huang, Yi-Chun, Chiang, Hsin-Chien, Chi, Mau-Shin, Chi, Chau-Hwa, Wang, Hsin-Ell, Kao, Shang-Jyh
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295413/
https://ncbi.nlm.nih.gov/pubmed/27486756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10873
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