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Heterogeneity of tumor cells in terms of cancer-initiating cells
Tumors derive from a single cell clone but consist of heterogeneous cell subpopulations with diverse features and functions. A limited number of subclones with a selective advantage can initiate tumors when inoculated into immunocompromised mice, and are called cancer-initiating cells (CICs). CICs c...
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| Udgivet i: | J Toxicol Pathol |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Japanese Society of Toxicologic Pathology
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5293686/ https://ncbi.nlm.nih.gov/pubmed/28190919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.2016-0056 |
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