EpEX/EpCAM and Oct4 or Klf4 alone are sufficient to generate induced pluripotent stem cells through STAT3 and HIF2α

Epithelial cell adhesion molecule (EpCAM) was reported to be cleaved into extracellular domain of EpCAM (EpEX) and intracellular domain of EpCAM (EpICD). We previously reported that EpCAM serves as a potent stem cell marker which is highly and selectively expressed by undifferentiated rather than di...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Kuan, I.-I., Liang, Kang-Hao, Wang, Yi-Ping, Kuo, Ting-Wen, Meir, Yaa-Jyuhn James, Wu, Sareina Chiung-Yuan, Yang, Shang-Chih, Lu, Jean, Wu, Han-Chung
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291097/
https://ncbi.nlm.nih.gov/pubmed/28157205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41852
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