PDGFRα depletion attenuates glioblastoma stem cells features by modulation of STAT3, RB1 and multiple oncogenic signals

Platelet derived growth factor receptors (PDGFRs) play an important role in tumor pathogenesis, and they are frequently overexpressed in glioblastoma (GBM). Earlier we have shown a higher protein expression of PDGFR isoforms (α and β) in peritumoral-tissue derived cancer stem cells (p-CSC) than in t...

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發表在:Oncotarget
Main Authors: Cenciarelli, Carlo, Marei, Hany E., Felsani, Armando, Casalbore, Patrizia, Sica, Gigliola, Puglisi, Maria Ausiliatrice, Cameron, Angus J.M., Olivi, Alessandro, Mangiola, Annunziato
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2016
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Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288168/
https://ncbi.nlm.nih.gov/pubmed/27344175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10132
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