PDGFRα depletion attenuates glioblastoma stem cells features by modulation of STAT3, RB1 and multiple oncogenic signals

Platelet derived growth factor receptors (PDGFRs) play an important role in tumor pathogenesis, and they are frequently overexpressed in glioblastoma (GBM). Earlier we have shown a higher protein expression of PDGFR isoforms (α and β) in peritumoral-tissue derived cancer stem cells (p-CSC) than in t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Cenciarelli, Carlo, Marei, Hany E., Felsani, Armando, Casalbore, Patrizia, Sica, Gigliola, Puglisi, Maria Ausiliatrice, Cameron, Angus J.M., Olivi, Alessandro, Mangiola, Annunziato
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2016
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288168/
https://ncbi.nlm.nih.gov/pubmed/27344175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10132
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